Procaine penicillin

  • Description
Procaine penicillin
 
Description:
 
The combination of procaine penicillin G and dihydrostreptomycin acts additive and in some cases synergistic. Procaine penicillin G is a small-spectrum penicillin with a bactericidal action against mainly Gram-positive bacteria like Clostridium, Corynebacterium, Erysipelothrix, Listeria, penicillinase-negative Staphylococcus and Streptococcus spp. Dihydrostreptomycin is an aminoglycoside with a bactericidal action against mainly Gram-negative bacteria like E. coli, Campylobacter, Klebsiella, Haemophilus, Pasteurella and Salmonella spp.
 
Composition:
 
Contains per ml.:
 
Procaine penicillin G 200 000 IU.
 
Dihydrostreptomycin sulphate 200 mg.
 
Solvents ad. 1 ml.
 
Indications:
 
Arthritis, mastitis and gastrointestinal, respiratory and urinary tract infections caused by penicillin and dihydrostreptomycin sensitive micro-organisms, like Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Klebsiella, Listeria, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. in calves, cattle, goats, sheep and swine.
 
Contra indications:
 
Hypersensitivity to penicillins, procaine and/or aminoglycosides.
 
Administration to animals with a seriously impaired renal function.
 
Concurrent administration of tetracyclines, chloramphenicol, macrolides and lincosamides.
 
Side effects:
 
Administration of therapeutic dosages of procaine penicillin G can result in abortion in sows.
 
Ototoxity, neurotoxicity or nephrotoxicity.
 
Hypersensitivity reactions.
 
Dosage:
 
For intramuscular administration:
 
Cattle : 1 ml per 20 kg body weight for 3 days.
 
Calves, goats, sheep and swine : 1 ml per 10 kg body weight for 3 days.
 
Shake well before use and do not administer more than 20 ml in cattle, more than 10 ml in swine and more than 5 ml in calves, sheep and goats per injection site.
 
Withdrawal times:
 
- For kidney: 45 days.
 
- For meat: 21 days.
 
- For milk: 3 days.
 
Warning:
 
Keep out of reach of children.
 
Packing:
 
Vial of 50 and 100 ml.